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Last updated: April 21, 2014

OPRU Publications and Presentations


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2014

Publications

Caritis, S. N., Venkataramanan, R., Thom, E., Harper, M., Klebanoff, M. A., Sorokin, Y., Thorp, J. M., Jr, Varner, M.W., Wapner, R. J., Iams, J. D., Carpenter, M. W., Grobman, W. A., Mercer, B. M,, Sciscione, A., Rouse, D.J., & Ramin, S; Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network and Obstetric-Fetal Pharmacology Research Units Network. (2014). Relationship between 17-alpha hydroxyprogesterone caproate concentration and spontaneous preterm birth. American Journal of Obstetrics and Gynecology, 210(2):128.e1-6. doi: 10.1016/j.ajog.2013.10.008. [Epub 2013 Oct 7]. (PMID: 24113254)

Chang J., Zhao Y., Zhao W., Venkataramanan R., Caritis S.N., Obstetrical-Fetal Pharmacology Research Units Network. Quality assessment of compounded 17-hydroxyprogesterone caproate. American Journal of Obstetrics and Gynecology. 2014 Jan:210(1).e1-7.doi: 10.1016/j.ajog.2013.09.039. Epub 2013 Nov 4. (PMID: 24200163).

Rytting E, Nanovskaya T.N., Wang X., Vernikovskaya D.I., Clark S.M., Cochran M., Abdel-Rahman S.M., Venkataramanan R., Caritis S.N., Hankins G.D., Ahmed M.S. Pharmacokinetics of indomethacin in Pregnancy. Clinical Pharmacokinet. [Epub ahead of print, 2014 Feb 4]. (PMID: 24493205).

2013

Publications

Caritis, S. N., & Hebert, M. F. (2013). A Pharmacologic Approach to the Use of Glyburide in Pregnancy. Obstetrics and Gynecology, 121(6), 1309-1312. doi: 10.1097/AOG.0b013e31829007f0. (PMID: 23812467).

Caritis, S. N., Zhao, Y., Bettinger, J., & Venkataramanan, R. (2013, February 20). Qualitative and quantitative measures of various compounded formulations of 17-alpha hydroxyprogesterone caproate. American Journal of Obstetrics and Gynecology. 2013 Jun:208(6):470.e1-5.doi: 10.1016/j.ajog.2013.02.028 Epub 2013 Feb20. (PMID: 23453884).

Caritis, S. N., Zhao, Y., Venkataramanan, R., & Bettinger, J. (2013, April 30). Reply. American Journal of Obstetrics and Gynecology. [Epub ahead of print]. doi: pii: S0002-9378(13)00472-9. 10.1016/j.ajog.2013.04.038. (PMID: 23643571).

Clark, S. N., & Hankins, G. D. (2013). Antenatal thyroid disease and pharmacotherapy in pregnancy. In D. Mattison (Ed.), Clinical pharmacology in pregnancy. London, UK: Elsevier.

Costantine, M. M., Cleary, K., & Eunice Kennedy Shriver National Institute of Child Health and Human Development OPRU Network. (2013). Pravastatin for the prevention of preeclampsia in high-risk pregnant women.Obstetrics and Gynecology, 121(2 Pt1), 349-353. doi: http://10.1097/AOG.0b013e31827d8ad5.(PMID: 23344286).

Cuppett, C. D., Zhao, Y., Caritis, S., Zhang, S., Zhao, W., & Venkataramanan, R. (2013). Effect of endogenous steroid hormones on 17-alpha-hydroxyprogesterone caproate metabolism. American Journal of Obstetrics and Gynecology, 208(1), 86.e1-86.e6. doi: 10.1016/j.ajog.2012.09.021. [Epub 2012 Sep 28].(PMID: 23063018).

Haas, D. M., Dantzer, J., Lehmann, A. S., Philips, S., Skaar, T. C., McCormick, C. L., Hebbring, S. J., Jung, J., & Li, L. (2013). The impact of glucocorticoid polymorphisms on markers of neonatal respiratory disease after antenatal betamethasone administration. American Journal of Obstetrics and Gynecology, 208(3), 215.e1-215.e6. doi: 10.1016/j.ajog.2012.12.031. [Epub 2013 Jan 4]. (PMID: 23295978).

Haas, D. M., & Flockhart, D. A. (2013). Pharmacogenomics in pregnancy. In D. R. Mattison (Ed.), Clinical pharmacology during pregnancy (pp. 113-128). London, UK: Elsevier, Inc.

Haas, D. M., Quinney, S. K., Clay, J., Renbarger, J. L., Hebert, M. F., Clark, S., Umans, J., & Caritis, S. N., for the Obstetric-Fetal Pharmacology Research Units Network. (2013). Nifedipine pharmacokinetics are influenced by CYP3A5 genotype when used as a preterm labor tocolytic. American Journal of Perinatology. 30(4):275-81. doi: 10.1055/s-0032-1323590. [Epub 2012 Aug 8].(PMID:22875663).

Hays, K. E., Ryu, R. J., Swisher, E. M., Reed, E., McManus, T., Rybeck, B., Petros, W. P., & Hebert, M. F. (2013). Duration of cisplatin excretion in breast milk. Journal of Human Lactation. 29(4):469-72. doi: 10.1177/0890334413479671. [Epub 2013 Mar 14]. (PMID: 23492761).

Hebert, M. F. (2013). Impact of pregnancy on maternal pharmacokinetics of medications. In D. R. Mattison (Ed.), Clinical pharmacology during pregnancy. London, Elsevier, Inc.

Hebert, M. F., Zheng, S., Hays, K., Shen, D. D., Davis, C. L., Umans, J. G., Miodovnik, M., Thummel, K. E., & Easterling, T. R. (2013). Interpreting tacrolimus concentrations during pregnancy and postpartum. Transplantation, 95(7), 908-915. doi: 10.1097/TP.0b013e318278d367. (PMID: 23274970).

Ke, A. B., Nallani, S. C., Zhao, P., Rostami-Hodjegan, A., Isoherranen, N., & Unadkat, J. D. (2013). A physiologically based pharmacokinetic model to predict disposition of CYP2D6 and CYP1A2 metabolized drugs in pregnant women. Drug Metabolism and Disposition, 41(4):801-13. doi: 10.1124/dmd.112.050161. [Epub 2013 Jan 25]. (PMID: 23355638).

Matok, I., Clark, S., Caritis, S., Miodovnik, M., Umans, J., Hankins, G., & Koren, G. (2013). Comparing the pharmacokinetics of doxylamine/pyridoxine delayed-release combination in nonpregnant women of reproductive age and women in the first trimester of pregnancy. Journal of Clinical Pharmacology, 53(3), 334-338. doi: 10.1177/0091270012445207. [Epub 2013 Jan 24]. (PMID: 23444286).

Nanovskaya, T. N., Patrikeeva, S. L., Paul, J., Costantine, M. M., Hankins, G. D., & Ahmed, M. S. (2013). Transplacental transfer and distribution of pravastatin. American Journal of Obstetrics and Gynecology 209(4):373.e1-5. doi: 10.1016/j.ajog.2013.05.038. (PMID: 24070396).

Pillai, V. C., Strom, S. C., Caritis, S. N., & Venkataramanan, R. (2013). A sensitive and specific CYP cocktail assay for the simultaneous assessment of human cytochrome P450 activities in primary cultures of human hepatocytes using LC-MS/MS. Journal of Pharmaceutical and Biomedical Analysis, 74, 126-132. doi: 10.1016/j.jpba.2012.10.016. [Epub 2012 Oct 22] (PMID: 23245243).

Rytting, E., & Ahmed, M. S. (2013). Fetal drug therapy. In D. R. Mattison (Ed.), Clinical pharmacology during pregnancy. London, UK: Elsevier, Inc.

Sharma, S., Ellis, E. C., Gramignoli, R., Dorko, K., Tahan, V., Hansel, M., Mattison, D. R., Caritis, S. N., Hines, R. N., Venkataramanan, R., & Strom, S. C. (2013). Hepatobiliary disposition of 17-OHPC and taurocholate in fetal human hepatocytes: A comparison with adult human hepatocytes. Drug Metabolism and Disposition, 41(2), 296-304. doi: 10.1124/dmd.112.044891. [Epub 2012 Nov 5]. (PMID: 23129211).

Wang, X., Rytting, E., Abdelrahman, D. R., Nanovskaya, T. N., Hankins, G. D., & Ahmed, S. (2013). Quantitative determination of famotidine in human maternal plasma, umbilical cord plasma and urine using high-performance liquid chromatography-mass spectrometry. Biomedical Chromatography. 27(7), 866-73. doi: 10.1002/bmc.2873. [Epub 2013 Feb 12]. (PMID: 23401067).

Wang, X., Vernikovskaya, D. I., Nanovskaya, T. N., Rytting, E., Hankins, G. D., & Ahmed, M. S. (2013). A liquid chromatography method with single quadrupole mass spectrometry for quantitative determination of indomethacin in maternal plasma and urine of pregnant patients. Journal of Pharmaceutical and Biomedical Analysis, 78-79, 123-128. doi: 10.1016/j.jpba.2013.02.006. [Epub 2013 Feb 15]. (PMID: 23474812).

Zheng, S., Easterling, T. R., Hays, K., Umans, J. G., Miodovnik, M., Clark, S., Calamia, J. C., Thummel, K. E., Shen, D. D., Davis, C. L., Hebert, M. F. (2013, March 26). Tacrolimus Placental Transfer at Delivery and Neonatal Exposure through Breast Milk. British Journal of Clinical Pharmacology. 76(6), 988-96. doi: 10.1111/bcp.12122. (PMID: 23528073).

Presentations

Haas, D. M., Lai, D., Sharma, S., Glassburn, J., Tantisira, K., & Foroud, T. (2013, March). Steroid pathway genes and neonatal respiratory distress after betamethasone use in anticipated preterm birth. Poster presentation at Annual Meeting, American Society for Clinical Pharmacology and Therapeutics, Indianapolis, IN.

Lee, N., Hebert, M. F., Easterling, T. R., Liang, J., Rice, K., & Wang, J. (2013, April). The Organic Cation Transporter 3 (OCT3) facilitates fetal disposition of metformin during pregnancy. Presentation at The Division for Drug Metabolism of The American Society for Pharmacology and Experimental Therapeutics (ASPET) Annual Meeting.

Shuster, D., Risler, L., Liang, J., Thummel, K., Hebert, M., Shen, D., & Mao, Q. (2013, May). Gestational age-dependent trends in maternal-fetal glyburide pharmacokinetics in pregnant mice. The American Conference on Pharmacometrics (ACoP), Fort Lauderdale, FL.

2012

Publications

Caritis, S. N., Sharma, S., Venkataraman, R., Hankins, G., Miodovnik, M., Hebert, M. F., Umans, J. G., Benedetti, T., Mattison, D., Zajicek, A., Fischer, D., Jackson, A., & Eunice Kennedy Shriver National Institute of Child Health and Human Development Obstetrical-Fetal Pharmacology Research Units Network. (2012). Pharmacology and placental transport of 17-hydroxyprogesterone caproate in singleton gestation. American Journal of Obstetrics and Gynecology, 207, 398.e1–398.e8. doi: 10.1016/j.ajog.2012.08.015. [Epub 2012 Aug 16].(PMID: 22967833).

Clark, S. M., Costantine, M. M., & Hankins, G. D. V. (2012). Review of NVP and HG and early pharmacotherapeutic intervention. Obstetrics and Gynecology International, 2012, 252676. doi: 10.1155/2012/252676. [Epub 2011 Nov 24]. (PMID: 22190950).

Costantine, M. M., Matok, I., Chiossi, G., Clark, S., Miodovnik, M., Umans, J. G., Caritis, S., Hankins, G. D. V., & Koren, G. (2012). Determinants of adherence to delayed-release doxylamine and pyridoxine in patients with nausea and vomiting of pregnancy. Therapeutic Drug Monitoring, 34(5), 569-573. (PMID: 22972538).

Endicott, S., & Haas, D. M. (2012, August). The current state of therapeutic drug trials in pregnancy. Clinical Pharmacology and Therapeutics, 92(2), 149-150. doi: 10.1038/clpt.2012.81. (PMID: 22814658).

Fokina, V. M., Zharikova, O. L., Hankins, G. D., Ahmed, M. S., & Nanovskaya, T. N. (2012). Metabolism of 17alpha-hydroxyprogesterone caproate by human placental mitochondria. Reproduction Science, 19(3), 290-297. (PMID: 22138546).

Haas, D. M., Caldwell, D. M., Kirkpatrick, P., McIntosh, J. J., & Welton, N. J. (2012). Tocolytic therapy for preterm delivery: A systematic review and network meta-analysis. BMJ, 345, e6226. doi: 10.1136/bmj.e6226. (PMID: 23048010).

Haas, D. M., & D’Alton, M. (2012). Higher dose or different drug? Pharmacogenetics and other reasons why drugs can fail in pregnancy. Obstetrics and Gynecology, 120(5), 1176-1179. doi: http://10.1097/AOG.0b013e3182698538. (PMID: 23090536).

Haas, D. M., Lehmann, A. S., Skaar, T., Philips, S., McCormick, C. L., Beagle, K., Hebbring, S. J., Dantzer, J., Li, L., & Jung, J. (2012). The impact of drug metabolizing enzyme polymorphisms on outcomes after antenatal corticosteroid use. American Journal of Obstetrics and Gynecology, 206(5), 447.e17-447.e24. doi: 10.1016/j.ajog.2012.02.016. [Epub 2012 Feb 28]. (PMID: 22445700).

Haas, D. M., Quinney, S. K., McCormick, C. L., Jones, D. R., & Renbarger, J. L. (2012). A pilot study of the impact of genotype on nifedipine pharmacokinetics when used as a tocolytic. The Journal of Maternal-Fetal & Neonatal Medicine, 25(4), 419-423. doi: 10.3109/14767058.2011.583700. [Epub 2011 Jun 7]. (PMID: 21644845).

Haas, D. M., & Renbarger, J. L. Pharmacogenetics of obstetric therapeutics. In R. B. Altman, D. Flockhart, & D. B. Goldstein (Eds.), Principles of pharmacogenetics and pharmacogenomics (pp. 202-216). Cambridge: Cambridge University Press.

Harirah, H. M., Borahay, M. A., Zaman, W., Ahmed, M. S., & Hankins, G. D. (2012). Increased apoptosis in chorionic trophoblasts of human fetal membranes with labor at term. International Journal of Clinical Medicine, 3, 136-142.

Koren, G., Clark, S., & Matsui, D. (2012). Drugs during pregnancy and lactation: New solutions to serious challenges. Obstetrics and Gynecology International, , 206179. doi: 10.1155/2012/206179. [Epub 2012 Mar 19]. (PMID: 22529853).

Nader, A. M., Caritis, S. N., Hebert, M. F., Clark, S. M., Flockhart, D. A., & Quinney, S. K. (2012). Compartmental pharmacokinetics of immediate release nifedipine in pregnancy: Variability in absorption. Clinical Pharmacology and Therapeutics, 91(S1), PIII-109.

Nanovskaya, T. N., Patrikeeva, S. L., Zhan, Y., Fokina, V. M., Hankins, G. D., & Ahmed, S. (2012). Transplacental transfer of vancomycin and televancin. American Journal of Obstetrics and Gynecology, 207(4), 331.e1.6. doi: 10.1016/j.ajog.2012.06.064. [Epub 2012 Aug 3]. (PMID: 22867688).

Nanovskaya, T. N., Patrikeeva, S. L., Zhan, Y., Hankins, G. D., & Ahmed, M. S. (2012). Transplacental transfer of oseltamivir carboxylate. The Journal of Maternal-Fetal & Neonatal Medicine, 25(11), 231-235. doi: 10.3109/14767058.2012.693993. [Epub 2012 Jun 7]. (PMID: 22590979).

Quinney, S. K., Mohamed, A. N., Hebert, M. F., Haas, D. M., Clark, S., Umans, J. G., Caritis, S. N., & Li, L. (2012). A semi-mechanistic metabolism model of CYP3A substrates in pregnancy: Predicting changes in midazolam and nifedipint pharmacokinetics. CPT: Pharmacometrics & Systems Pharmacology,, 1, e2. [Published online 26 September 2012]. doi: 10.1038/psp.2012.5. (PMID: 23835882)

van Hasselt, J. G., Andrew, M. A., Hebert, M. F., Tarning, J., Vicini, P., & Mattison, D. R. (2012). The status of pharmacometrics in pregnancy: Highlights from the 3rd American Conference on Pharmacometrics. British Journal of Clinical Pharmacology, 74(6), 932-939. doi: 10.1111/j.1365-2125.2012.04280.x. (PMID: 22452385).

Zheng, S., Easterling, T. R., Umans, J. G., Miodovnik, M., Calamia, J. C., Thummel, K. E., Shen, D. D., Davis, C. L., & Hebert, M. F. (2012). Pharmacokinetics of tacrolimus during pregnancy. Therapeutic Drug Monitoring, 34(6), 660-670. doi: 10.1097/FTD.0b013e3182708edf. (PMID: 23007747).

Presentations

Ahmed, W., Mund, J., Case, J., & Haneline, L. S. (2012, October). The role of endothelial progenitor cell numbers in infants and children on vascular reactivity. Midwest Society for Pediatric Research, Columbus, OH.

Blue, E., Ballman, K., Khan, S., & Haneline, L. S. (2012, May). Consequences of gestational diabetes, aging, and postnatal dietary stress on metabolism and hematopoiesis. Pediatric Academic Society Meeting, Boston, MA.

Haas, D. M. (2012, May 11). Betamethasone pharmacogenetics: Is individualized antenatal corticosteroid therapy on the horizon? 2nd Annual Neonatal Symposium, Indianapolis, IN.

Haas, D. M. (2012, October). The impact of glucocorticoid polymorphisms on outcomes indicating neonatal respiratory morbidity severity after betamethasone therapy for preterm labor. Central Association of Obstetricians and Gynecologists annual meeting, Chicago, IL.

Haneline, L. S. (2012). Exploring cellular biomarkers in pregnancy and pediatrics. Neonatal-Perinatal Medicine Research Seminar, Children’s Hospital of Philadelphia, Philadelphia, PA.

Shuster, D. L., Bammler, T. K., Beyers, R. P., MacDonald, J., Farin, F., Hebert, M. F., Thummel, K. E., & Mao, Q. (2012, July). Gene expression profiling of maternal liver, kidney, and small intestine in pregnant mice during pregnancy. Gordon Research Conference: Drug Metabolism, Holderness, MA.

Wang, X., Vernikovskaya, D. I., Ahmed, M. S., Hankins, G. D. V., & Nanovskaya, T. N. (2012, September). Distribution of bupropion and its major metabolites in maternal vein, umbilical cord and placental tissue: A pilot study. ACCP Annual Meeting, San Diego, CA.

Zacharias, N., Nanovskaya, T. N., Hankins, G. D. V., & Ahmed, M. S. (2012, February). Maternal-fetal gestational characteristics and microsomal aromatase activity in human placentas. Society for Maternal-Fetal Medicine 32nd Annual Meeting, Dallas, TX.

2011

Publications

Acosta, J. C., Haas, D. M., Saha, C. K., Dimeglio, L. A., Ingram, D. A., & Haneline, L. S. (2011). Gestational diabetes mellitus alters maternal and neonatal circulating endothelial progenitor cell subsets. American Journal of Obstetrics and Gynecology, 204, 254.e8-e15. doi: 10.1016/j.ajog.2010.10.913. [Epub 2010 Dec 16]. (PMID: 21167470).

Beigi, R. H., Kelong, H., Venkataramanan, R., Hankins, G. D., Clark, S., Herbert, M. F., Easterling, T., Zajicek, A., Ren, Z., Mattison, D. R., & Caritis, S. N. (2011). Pharmacokinetics of Oseltamivir among pregnant and non-pregnant women. American Journal of Obstetrics and Gynecology, 204(6 Suppl 1), S84-88. doi: 10.1016/j.ajog.2011.03.002. [Epub 2011 Mar 9]. (PMID: 21492826).

Clark, S. M., & Nakad, R. (2011). Pharmacotherapeutic management of nicotine dependence in pregnancy. Obstetrics and Gynecology Clinics of North America,38(2), 297-311. doi: 10.1016/j.ogc.2011.02.017. (PMID: 21575802).

Haas, D. M. (2011). From no to yes: The history and ethics of including pregnant women in clinical trials. Clinical Investigation, 1(10), 1349-1351.

Haas, D. M. (2011). Opioid exposure and birth defects. American Journal of Obstetrics and Gynecology, 205(3), e8-e10. author reply e10-1. doi: 10.1016/j.ajog.2011.06.031. [Epub 2011 Jun 15]. (PMID: 22071073).

Haas, D. M., Daum, M., Skaar, T., Philips, S., Miracle, D., & Renbarger, J. L. (2011). Human breast milk as a source of DNA for amplification. Journal of Clinical Pharmacology, 51(4), 616-619. doi: 10.1177/0091270010370847. [Epub 2010 May 24]. (PMID: 20498289).

Haas, D. M., Gallauresi, B., Shields, K., Zeitlin, D., Clark, S. M., Hebert, M. F., Ren, A., Nallani, S. C., Meslin, E. M., Feibus, K. B., Koren, G., Goebel, W. S., Easterling, T., Denne, A. C., Flockhart, D. A., & Renbarger, J. L. (2011). Pharmacotherapy and pregnancy: Highlights from the Third International Conference for Individualized Pharmacotherapy in Pregnancy. Clinical and Translational Science, 4, 204-209. doi: 10.1111/j.1752-8062.2011.00280.x. (PMID: 21707952).

Haas, D. M., Sischy, A. C., McCullough, W., & Simsiman, A. J. (2011). Maternal ethnicity influences on neonatal respiratory outcomes after antenatal corticosteroid use for anticipated preterm delivery. The Journal of Maternal-Fetal & Neonatal Medicine, 24(3), 516-520. doi: 10.3109/14767058.2010.506228. [Epub 2010 Jul 30]. (PMID: 20672908).

Lehmann, A. S., Haas, D. M., McCormick, C. L., Skaar, T. C., & Renbarger, J. L. (2011). Collection of human genomic DNA from neonates: A comparison between umbilical cord blood and buccal swabs. American Journal of Obstetrics and Gynecology, 204(4), 362.e1-362.e6. doi: 10.1016/j.ajog.2010.12.013. [Epub 2011 Feb 16]. (PMID: 21324432).

Nanovskaya, T. N., Hankins, G. D. V., & Ahmed, M. S. (2011). The placenta as a functional barrier to fetal drug exposure. In H. Kay, D. M. Nelson, & Y. Wang (Eds.), The placenta from development to disease (pp. 303-309). Hoboken, NJ: Wiley-Blackwell.

Simhan, H. N., Himes, K. P., Venkataramanan, R., & Bodnar, L. M. (2011, July). Maternal serum folate species in early pregnancy and lower genital tract inflammatory milieu. American Journal of Obstetrics and Gynecology, 205(1), 61.e1-61.e7. doi: 10.1016/j.ajog.2011.03.039. [Epub 2011 Mar 26]. (PMID: 21600548).

Walker, A. A., Dickmann, L., & Isoherranen, N. (2011, January). Pregnancy decreases rat CYP1A2 activity and expression. Drug Metabolism and Disposition, 39(1), 4-7. (PMID: 20921303).

Presentations

DiGuiseppe, R., Derr-Yellin, E., Acosta, J. C., & Haneline, L. S. (2011, May). Gestational diabetes induces altered function of neonatal endothelial colony forming cell. Pediatric Academic Society Meeting, Denver, CO.

Haas, D. M. (2011, March 18). The impact of genotype on neonatal outcomes from antenatal corticosteroid therapy for preterm labor. Society for Gynecologic Investigation, Miami, FL.

Haas, D. M. (2011, October). Assessing the quality of the evidence for preterm labor tocolysis trials. Cochrane Collaboration, 2011 Combined Cochrane and Campbell Colloquia, Keystone, CO.

Haneline, L. S. (2011). Diabetes in pregnancy: Maternal and fetal progenitor cell defects. American Academy of Pediatrics Annual Seminar on Neonatal/Perinatal Medicine, Santa Fe, NM.

Quinney, S. K., Hebert, M., & Li, L. (2011, April). A semi-mechanistic pharmacokinetic model of midazolam in pregnancy: Alteration of CYP3A activity. American Conference on Pharmacometrics. San Diego, CA.

Wang, X., Rytting, E., Nanovskaya, T. N., Patrikeeva, S. L., Clark, S., Jasek, M. B., Venkataramanan, R., Caritis, S., Hankins, G. D. V., & Ahmed, M. S. (2011, February). Pharmacokinetics of indomethacin in pregnant women with preterm labor. Society for Maternal Fetal Medicine 31st Annual Meeting, San Francisco, CA.

Wang, X., Zhan, Y., Rytting, E., Patrikeeva, S. L., Nanovskaya, T. N., Clark, S., Jackson, A., Venkataramanan, R., Caritis, S., Hankins, G. D. V., & Ahmed, M. S. (2011, February). Pharmacokinetics of famotidine in pregnant women. Society for Maternal Fetal Medicine 31st Annual Meeting, San Francisco, CA.

Yep, T., Eyal, S., Easterling, T. R., Shen, D. D., Kelly, E., Hankins, G. D. V., Caritis, S., Risler, L., & Hebert, M. F. (2011, October). The pharmacokinetics of metoprolol during pregnancy. American College of Clinical Pharmacy Annual Meeting, Pittsburgh PA.

Zhan, Y., Wang, X., Rytting, E., Patrikeeva, S. L., Nanovskaya, T. N., Clark, S., Jackson, A., Venkataramanan, R., Caritis, S., Hebert, M., Easterling, T. R., Hankins, G. D. V., & Ahmed, M. S. (2011, February). Pharmacokinetics of bupropion in pregnant women. Society for Maternal Fetal Medicine 31st Annual Meeting, San Francisco, CA.

2010

Publications

Bodnar, L. M., Himes, K. P., Venkataramanan, R., Chen, J. Y., Evans, R. W., Meyer, J. L., & Simhan, H. N. (2010, October). Maternal serum folate species in early pregnancy and risk of preterm birth. American Journal of Clinical Nutrition, 92(4), 864-871. [Epub 2010 Aug 25]. (PMID: 20739422).

Claessens, A., Risler, L., Eyal, S., Shen, D., Easterling, T., & Hebert, M. (2010, September). CYP2D6 mediates 4-hydroxylation of clonidine in vitro: Implication for pregnancy-induced changes in clonidine clearance. Drug Metabolism and Disposition, 38(9), 1393-1396. [Epub 2010 Jun 22]. (PMID: 20570945).

Chung, F. S., Eyal, S., Muzi, M., Link, J. M., Mankoff, D. A., Kaddoumi, A., O’Sullivan, F., Hsiao, P., & Unadkat, J. D. (2010, January). Positron emission tomography imaging of tissue P-glycoprotein during pregnancy in the non-human primate. British Journal of Pharmacology, 159(2), 394-404. (PMID: 20002098).

Eyal, S., Easterling, T. R., Carr, D., Umans, J. G., Miodovnik, M., Hankins, G. D., Clark, S. M., Risler, L., Wang, J., Kelly, E. J., Shen, D. D., & Hebert, M. F. (2010). Pharmacokinetics of Metformin during pregnancy. Drug Metabolism and Dispositio, 38, 833-840. (PMID: 20118196).

Eyal, S., Kim, J. D., Anderson, G. D., Buchanan, M. L., Brateng, D. A., Carr, D., Woodrum, D. E., Easterling, T. R., & Hebert, M. F. (2010, November). Atenolol Pharmacokinetics and excretion in breast milk during the first 6-8 months postpartum. Journal of Clinical Pharmacology, 50(11), 1301-1309. [Epub 2010 Feb 9]. (PMID: 20145263).

Hemauer, S. J., Patrikeeva, S. L., Nanovskaya, T. N., Hankins, G. D., & Ahmed, M. S. (2010, April). Role of human placental apical membrane transporters in the efflux of glyburide, rosiglitazone, and metformin. American Journal of Obstetrics and Gynecology, 202(4), 383.e1-383.e7. (PMID: 20350646).

Hemauer, S. J., Nanovskaya, T. N., Abdel-Rahman, S. Z., Patrikeeva, S. L., Hankins, G. D., & Ahmed, M. S. (2010, March). Modulation of human placental P-glycoprotein expression and activity by MDR1 gene polymorphisms. Biochemical Pharmacology, 79(6), 921-925. (PMID: 19896927).

Koren, G., Clark, S. M., Hankins, G. D. V., Caritis, S. N., Miodovnik, M., & Mattison, D. R. (2010, December). Effectiveness of delayed-release doxylamine and pyridoxine for nausea and vomiting of pregnancy: A randomized placebo-controlled trial. American Journal of Obstetrics and Gynecology, 203(6), 571.e1-571.e7. [Epub 2010 Sep 16]. (PMID: 20843504).

Rothenberger, S., Carr, D., Brateng, D., Hebert, M., & Easterling, T. (2010). Pharmacodynamics of clonidine therapy in pregnancy: A heterogeneous maternal response impacts fetal growth. American Journal of Hypertension, 23, 1234-1240. (PMID: 20725050).

Sharma, S., Ellis, E. C., Dorko, K., Zhang, S., Mattison, D. R., Caritis, S. N., Venkataramanan, R., & Strom, S. C. (2010, May). Metabolism of 17alpha-hydroxyprogesterone caproate, an agent for preventing preterm birth, by fetal hepatocytes. Drug Metabolism and Disposition, 38(5), 723-727. [Epub 2010 Jan 22]. (PMID: 20097724).

Wang, X., Nanovskaya, T. N., Zhan, Y., Abdel-Rahman, S. M., Jasek, M. B., Hankins, G. D. V., & Ahmed, M. S. (2011, March). Pharmacokinetics of metronidazole in pregnant patients with bacterial vaginosis. The Journal of Maternal-Fetal & Neonatal Medicine, 24(3), 444-448. [Epub 2010 Jul 7]. (PMID: 20608802).

Zharikova, O. L., Nanovskaya, T. N., & Ahmed, M. S. (2010). Biotransformation of medications by human placenta. In S. J. Yaffe & J. V. Aranda (Eds.), Neonatal and Pediatric Pharmacology; Therapeutic Principles in Practice, 4th Edition (pp. 144-153). Philadelphia, PA: Lippincott Williams & Wilkins.

Zhou, L., Naraharisetti, S. B., Liu, L., Wang, H., Lin, Y. S., Isoherranen, N., Unadkat, J. D., Hebert, M. F., & Mao, Q. (2010, May). Contributions of human cytochrome P450 enzymes to Glyburide metabolism. Biopharmaceutics and Drug Disposition, 31(4), 228-242. (PMID: 20437462).

Zhou, L., Zhang, Y., Hebert, M., Unadkat, J., & Mao, Q. (2010, September). Increased Glyburide Clearance in the Pregnant Mouse Model. Drug Metabolism and Disposition, 38(9), 1403-1406. [Epub 2010 Jun 17]. (PMID: 20558597).

Presentations

Ballman, K., Khan, S., Kono, T., Evans-Molina, C., & Haneline, L. S. (2010, May). Consequences of gestational diabetes and adult dietary stress in the aged rat offspring. Pediatric Academic Society, Vancouver, British Columbia, Canada.

Haneline, L. S. (2010). Redox regulation of stem cells. Gordon Research Conference, Thiol-based Redox Regulation and Signaling, Lucca, Italy.

Haneline, L. S. (2010). Diabetes in pregnancy: Fetal effects that predispose to later cardiac disease. American Academy of Pediatrics District VIII Section on Perinatal Pediatrics Meeting, Boise, ID.

Harirah, H. M., Nekhayeva, I. A., & Ahmed, M. S. (2010, February). Differential expression of prostaglandin biosynthetic enzymes in human fetal membrane layers during pregnancy and labor. Society for Maternal-Fetal Medicine 30th Annual Meeting, Chicago, IL.

Harirah, H. M., Nekhayeva, I. A., & Ahmed, M. S. (2010, February). Role of prostaglandin influx and efflux transporters (PGT and MRP4) in human fetal membranes. Society for Maternal-Fetal Medicine 30th Annual Meeting, Chicago, IL.

Haas, D. M. (2010, September 4). Preterm labor- why we hand you babies too soon and what (if anything) we can do about it. Pediatric Academic Society, 34th Midwest Conference on Perinatal Research.

Haas, D. M. (2010, October 29). The impact of genotype on nifedipine pharmacokinetics when used as a tocolytic. Central Association of Obstetricians and Gynecologists, Annual Meeting Las Vegas, NV.

Hemauer, S. J., Patrikeeva, S. L., Nanovskaya, T. N., Hankins, G. D., & Ahmed, M. S. (2010, February). Multiple ABC transporters of human placental brush border membranes contribute to the efflux of glyburide, rosiglitazone, and metformin. Oral presentation, Society for Maternal Fetal Medicine 30th Annual Meeting, Chicago, IL.

Hemauer, S. J., Patrikeeva, S. L., Nanovskaya, T. N., & Ahmed, M. S. (2010, June). Role of p-glycoprotein and breast cancer resistance protein in the placental biodisposition of bupropion and its metabolic, OH-bupropion. College on Problems of Drug Dependence 72nd Annual Scientific Meeting, Scottsdale, AZ.

Wang, X., Zhan, Y., Rytting, E., Patrikeeva, S. L., Nanovskaya, T. N., Clark, S., Jackson, A., Venkataramanan, R., Caritis, S., Hankins, G. D. V., & Ahmed, M. S. (2010, September). Pharmacokinetics of famotidine during pregnancy and postpartum. American College of clinical Pharmacology 39th Annual Meeting, Baltimore, MD.

Zharikova, O. L., Fokina, V. M., Yan, R., Nanovskaya, T. N., Hankins, G. D. V., & Ahmed, M. S. (2010, February). Metabolism of 17a-hydroxyprogesteronecaproate (17-P) by human placental mitochondrial and microsomal enzymes. Society for Maternal Fetal Medicine 30th Annual Meeting, Chicago, IL.

2009

Publications

Buchanan, M. L., Easterling, T. R., Carr, D. B., Shen, D. D., Risler, L. J., Nelson, W. L., Mattison, D. R., & Hebert, M. F. (2009, April). Clonidine pharmacokinetics in pregnancy. Drug Metabolism and Disposition, 37(4), 702-705. (PMID: 19116263).

Eyal, S., Chung, F. S., Muzi, M., Link, J. M., Mankoff, D. A., Kaddoumi, A., O’Sullivan, F., Hebert, M. F., & Unadkat, J. D. (2009, May). Simultaneous PET imaging of P-glycoprotein inhibition in multiple tissues in the pregnant non-human primate. Journal of Nuclear Medicine, 50(5), 798-806. (PMID: 19403878).

Hebert, M. F., Ma, X., Naraharisetti, S. B., Krudys, K. M., Umans, J. G., Hankins, G. D., Caritis, S. N., Miodovnik, M., Mattison, D. R., Unadkat, J. D., Kelly, E. J., Blough, D., Cobelli, C., Ahmed, M. S., Snodgrass, W. R., Carr, D. B., Easterling, T. R., Vicini, P., & Obstetric-Fetal Pharmacology Research Unit Network. (2009, June). Are we optimizing gestational diabetes treatment with glyburide? The pharmacologic basis for better clinical practice. Clinical Pharmacology and Therapeutics, 85(6), 607–614. (PMID: 19295505).

Nanovskaya, T. N., Bowen, R. S., Patrikeeva, S. L., Hankins, G. D., & Ahmed, M. S. (2009, August). Effect of plasma proteins on buprenorphine transfer across dually perfused placental lobule. The Journal of Maternal-Fetal & Neonatal Medicine, 22(8), 646-653. (PMID: 19544152).

Zharikova, O. L., Fokina, V. M., Nanovskaya, T. N., Hill, R. A., Mattison, D. R., Hankins, G. D., & Ahmed, M. S. (2009, December 15). Identification of the major human hepatic and placental enzymes responsible for the biotransformation of glyburide. Biochemical Pharmacology, 78(12), 1483-1490. (PMID: 19679108).

Presentations

Haas, D. M., Hebert, M. F., Soldin, O. P., Flockhart, D. A., Madadi, P., Nocon, J. J., Chambers, C. D., Hankins, G. D., Clark, S., Wisner, K. L., Li, L., Renbarger, J. L., & Leraman, L. A. (2009, December). Pharmacotherapy and pregnancy: Highlights from the Second International Conference for Individualized Pharmacotherapy in Pregnancy. Clinical and Translational Science, 2(6), 439–443.

Haas, D. M. (2009, February 5). PREGMED: Personalized pharmacotherapy for women: Focus on SSRIs. North American Society for Psychosocial Obstetrics/ Marcé Society National Meeting.

2008

Publications

Andrew, M. A., Hebert, M. F., Vicini, P. (2008). Physiologically based pharmacokinetic model of midazolam disposition during pregnancy. Conference Proceedings: IEEE Engineering in Medicine and Biology Society, 2008, 5454-5457. (PMID: 19163951).

Dickmann, L. J., Tay, S., Senn, T. D., Zhang, H., Visone, A., Unadkat, J. D., Hebert, M. F., & Isoherranen, N. (2008, April 15). Changes in maternal liver Cyp2c and Cyp2d expression and activity during rat pregnancy. Biochemical Pharmacology, 75(8), 1677-1687. (PMID: 18342837).

Guo, T., Gu, J., Soldin, O. P., Singh, R. J., & Soldin, S. J. (2008, June). Rapid measurement of estrogens and their metabolites in human serum by liquid chromatography-tandem mass spectrometry without derivatization. Clinical Biochemistry, 41(9), 736-741. (PMID: 18358240).

Hemauer, S. J., Yan, R., Patrikeeva, S. L., Mattison, D. R., Hankins, G. D., Ahmed, M. S., & Nanovskaya, T. N. (2008, August). Transplacental transfer and metabolism of 17-alpha-hydroxyprogesterone caproate. American Journal of Obstetrics and Gynecology, 199(2), 169.e1-169.e5. (PMID: 18674659).

Jain, S., Zharikova, O. L., Ravindran, S., Nanovskya, T. N., Mattison, D. R., Hankins, G. D., & Ahmed, M. S. (2008, March). Glyburide metabolism by placentas of healthy and gestational diabetics. American Journal of Perinatology, 25(3), 169-174. [Epub 2008 Feb 25]. (PMID: 18300189).

Mikheev, A. M., Nabekura, T., Kaddoumi, A., Bammler, T. K., Govindarajan, R., Hebert, M. F., & Unadkat, J. D. (2008, November). Profiling gene expression in human placentae of different gestational ages: An OPRU Network and UW SCOR study. Reproduction Science, 15(9), 866-877. (PMID: 19050320).

Nanovskaya, T. N., Patrikeeva, S., Hemauer, S., Fokina, V., Mattison, D., Hankins, G. D., Ahmed, M. S., & OPRU Network. (2008, March). Effect of albumin on transplacental transfer and distribution of rosiglitazone and glyburide. Journal of Maternal Fetal & Neonatal Medicine, 21(3), 197-207. (PMID: 18297575).

Sharma, S., Ou, J., Strom, S., Mattison, D., Caritis, S., & Venkataramanan, R. (2008, September). Identification of enzymes involved in the metabolism of 17a-hydroxyprogesterone caproate: An effective agent for the prevention of preterm birth. Drug Metabolism and Disposition, 36(9), 1896-18902. (PMID: 18573861).

Simhan, H. N., Chiao, J. P., Mattison, D. R., & Caritis, S. N. (2008, January). Human decidual cell Toll-like receptor signaling in response to endotoxin: The effect of progestins. American Journal of Obstetrics and Gynecology, 198(1), 119.e1-119.e4. (PMID: 17936235).

Soldin, O. P., Dahlin, J., & O'Mara, D. M. (2008, February). Triptans in pregnancy. Therapeutic Drug Monitoring, 30(1), 5-9. (PMID: 18223456).

Soldin, O. P., Tonning, J. M., & Obstetric-Fetal Pharmacology Research Unit Network. (2008, May 15). Serotonin syndrome associated with triptan monotherapy. New England Journal of Medicine, 358(20), 2185-2186. (PMID: 18480219).

Unadkat, J. D., Chung, F., Sasongko, L., Whittington, D., Eyal, S., Mankoff, D., Collier, A. C., Muzi, M., & Link, J. (2008, November). Rapid solid-phase extraction method to quantify [(11)C]-verapamil, and its [(11)C]-metabolites in human and macaque plasma. Nuclear Medicine and Biology, 35(8), 911-917. (PMID: 19026953).

Yan, R., Fokina, V., Hankins, G. D., Ahmed, M. S., & Nanovskaya, T. N. (2008, February). The effect of esterases on 17alpha-hydroxyprogesteronecaproate. American Journal of Obstetrics and Gynecology, 198(2), 229.e1-229.e5. (PMID: 17936237).

Yan, R., Nanovskaya, T. N., Zharikova, O. L., Mattison, D. R., Hankins, G. D., & Ahmed, M. S. (2008, May 1). Metabolism of 17alpha-hydroxyprogesterone caproate by hepatic and placental microsomes of human and baboons. Biochemical Pharmacology, 75(9), 1848-1857. (PMID: 18329004).

Zhang, S., Mada, S. R., Sharma, S., Torch, M., Mattison, D., Caritis, S., & Venkataramanan, R. (2008, December 1). Simultaneous quantitation of 17a-hydroxyprogesterone caproate, 17a-hydroxyprogesterone and progesterone in human plasma using high-performance liquid chromatography-mass spectrometry (HPLC-MS/MS). Journal of Pharmaceutical and Biomedical Analysis, 48(4), 1174–1180. [Epub 2008 Aug 29]. (PMID: 18947956).

Zhou, L., Naraharisetti, S. B., Wang, H., Unadkat, J. D., Hebert, M. F., & Mao, Q. (2008, March). The breast cancer resistance protein (Bcrp1/Abcg2) limits fetal distribution of glyburide in the pregnant mouse: An Obstetric-Fetal Pharmacology Research Unit Network and University of Washington Specialized Center of Research Study. Molecular Pharmacology, 73(3), 949–959. (PMID: 18079276).

Presentations

Hemauer, S. J., Yan, R., Patrikeeva, S. L., Mattison, D., Hankins, G. D. V., Ahmed, M. S., & Nanovskaya, T. N. (2008, January). Metabolism of 17a-hydroxyprogesterone caproate by the dually perfused human placental lobule. 28th Annual Meeting of the Society of Maternal-Fetal Medicine, Dallas, TX. (PMID: 18674659).

Ravindran, S., Zharikova, O. L., Nanovskaya, T. N., Hill, R., Mattison, D., Hankins, G. D. V., & Ahmed, M. S. (2008, April). Investigation of glyburide and its metabolites in urine and plasma of pregnant patients under treatment for gestational diabetes. American Chemical Society National Meeting, New Orleans, LA.

Zharikova, O. L., Fokina, V. M., Nanovskaya, T. N., Ravindran, S., Hill, R., Mattison, D., Hankins, G. D. V., & Ahmed, M. S. (2008, January). Identification of the major human hepatic and placental enzymes responsible for the metabolism of glyburide. 28th Annual Meeting of the Society for Maternal-Fetal Medicine, Dallas, TX.

Zharikova, O. L., Nanovskaya, T. N., Hankins, G. D. V., & Ahmed, M. S. (2008, September). In vivo and in vitro metabolism of glyburide by human placenta. International Federation of Placenta Associations 2008 Meeting, Seggau Castle, Austria.

2007

Publications

Andrew, M. A., Easterling, T. R., Carr, D. B., Shen, D., Buchanan, M. L., Rutherford, T., Bennett, R., Vicini, P., & Hebert, M. F. (2007, April). Amoxicillin pharmacokinetics, modeling and simulations of dosage strategies. Clinical Pharmacology and Therapeutics, 81(4), 547–556. (PMID: 17329990).

Gu, J., Soldin, O. P., & Soldin, S. J. (2007, December). Simultaneous quantification of free triiodothyronine and free thyroxine by isotope dilution tandem mass spectrometry.Clinical Biochemistry, 40(18), 1386-1391. (PMID: 17936741).

Kahric-Janicic, N., Soldin, S. J., Soldin, O. P., West, T., Gu, J., & Jonklaas, J. (2007, April). Tandem mass spectrometry improves the accuracy of free thyroxine measurements during pregnancy. Thyroid, 17(4), 303-311. (PMID: 17465859).

Katz, I., Kim, J., Gale, K., & Kondratyev, A. (2007, August). Effects of lamotrigine alone and in combination with MK-801, phenobarbital, or phenytoin on cell death in the neonatal rat brain. Journal of Pharmacology and Experimental Therapeutics, 322(2), 494-500. (PMID: 17483293).

Kim, J., Kondratyev, A., & Gale, K. (2007, October). Antiepileptic drug-induced neuronal cell death in the immature brain: Effects of carbamazepine, topiramate, and levetiracetam as monotherapy versus polytherapy. Journal of Pharmacology and Experimental Therapeutics, 323(1), 165-173. (PMID: 17636003).

Kim, J. S., Kondratyev, A., Tomita, Y., & Gale, K. (2007). Neurodevelopmental impact of antiepileptic drugs and seizures in the immature brain. Epilepsia, 48(Suppl 5), 19-26. (PMID: 17910577).

Naraharisetti, S. B., Kirby, B. J., Hebert, M. F., Easterling, T. R., & Unadkat, J. D. (2007, December 1). Validation of a sensitive LC-MS assay for quantification of glyburide and its metabolite 4-transhydroxy glyburide in plasma and urine: An OPRU Network study. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 860(1), 34–41. (PMID: 17980680).

Roesch, D., Malthankar-Phatak, G., Hintz, T., McCloskey, D., Sandberg, K., Maclusky, N., & Scharfman, H. (2007). A model of epilepsy during pregnancy in Sprague-Dawley rats. American Journal of Obstetrics and Gynecology, 197(6), S125.(Link).

Roesch, D., Shi, M., Shalkey, V., Spittler, J., Sandberg, K., Umans, J., & Miodovnik, M. (2007). Gestational changes in renal electrolyte transporters may increase lithium toxicity. American Journal of Obstetrics and Gynecology, 197(6), S125. (Link).

Soldin, O. P., & Aschner, M. (2007, September). Effects of manganese on thyroid hormones homeostatis: Potential links. Neurotoxicology, 28(5), 951–956. (PMID: 17576015).

Soldin, O. P., Soldin, D., & Sastoque, M. (2007, October). Gestation-specific thyroxine and thyroid stimulating hormone levels in the United States and worldwide. Therapeutic Drug Monitoring, 29(5), 553-559. (PMID: 17898643).

Zhang, S., Mada, S. R., Mattison, D., Caritis, S., Venkataramanan, R., & OPRU Network. (2007, September 1). Development and validation of a high-performance liquid chromatography-mass spectrometric assay for the determination of 17a-hydroxyprogesterone caproate (17-OHPC) in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 856(102), 141–147. (PMID: 17576102).

Zhang, S., Mada, S. R., Mattison, D., Caritis, S., Venkataramanan, R., & Obstetric-Fetal Pharmacology Research Unit Network. (2007, September 1). Development and validation of a high-performance liquid chromatography-mass spectrometric assay for the determination of 17alpha-hydroxyprogesterone caproate(17-OHPC) in human plasma. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 856(1–2), 141–147. [Epub 2007 Jun 2]. (PMID: 17576102).

Zharikova, O. L., Ravindran, S., Nanovskaya, T. N., Hill, R. A., Hankins, G. D., & Ahmed, M. S. (2007, June 15). Kinetics of glyburide metabolism by hepatic and placental microsomes of human and baboon. Biochemical Pharmacology, 73(12), 2012-2019. (PMID: 17462606).

Presentations

Harirah, H. M., Zaman, W., Ahmed, M. S., & Hankins, G. D. V. (2007, February). Effect of chorion-decidua on prostaglandin E2 production in human fetal membranes. 27th Annual Meeting of the Society for Maternal- Fetal Medicine, San Francisco, CA.

Hemauer, S. J., Patrikeeva, S. L., Hankins, G. D. V., Ahmed, M. S., & Nanovskaya, T. N. (2007, February). Human placental transfer of 17a-hydroxyprogestrone caproate. 27th Annual Meeting of the Society for Maternal- Fetal Medicine, San Francisco, CA.

Patrikeeva, S. L., Hemauer, S. J., Nanovskaya, T. N., Hankins, G. D. V., & Ahmed, M. S. (2007, February). Transplacental transfer and distribution of rosiglitazone. 27th Annual Meeting of the Society for Maternal- Fetal Medicine, San Francisco, CA.

Yan, R., Nanovskaya, T. N., Hankins, G. D. V., & Ahmed, M. S. (2007, February). The effect of esterases on 17a-hydroxyprogesterone caproate. 27th Annual Meeting of the Society for Maternal- Fetal Medicine, San Francisco, CA.

Zharikova, O. L., Ravindran, S., Nanovskaya, T. N., Hankins, G. D. V., & Ahmed, M. S. (2007, February). The role of the placenta in metabolism of glyburide in human and baboon. 27th Annual Meeting of the Society for Maternal- Fetal Medicine, San Francisco, CA.

2006

Publications

Clark, S. M., Saade, G. R., Snodgrass, W. R., & Hankins, G. D. (2006, August). Pharmacokinetics and pharmacotherapy of thionamides in pregnancy. Therapeutic Drug Monitoring, 28(4), 477-483. (PMID: 16885714).

Fitsanakis, V. A., Owens, S. E., dos Snatos, A. P. M., Soldin, O. P., & Aschner, M. (2006). Manganese transport and neurotoxicity. Metal Ions in Biology and Medicine, 9, 101-107.

Katz, I., Kim, J., Gale, K., & Kondratyev, A. (2006, December). Effects of Lamotrigine on Apoptotic Cell Death of the Neonatal Rat Brain. AES Abstract, 2.184. (Link).

Kim, J., Kondratyev, A., & Gale, K. (2006, December). Enhancement of Phenytoin-Induced Neuronal Death in Neonatal Rats by AEDs That Do Not Induce Neuronal Death When Given Alone. AES Abstract, 2.182. (Link).

Koren, G., & Soldin, O. (2006, February). Therapeutic drug monitoring of antithyroid drugs in pregnancy: The knowledge gaps. Therapeutic Drug Monitoring, 28(1), 12-13. (PMID: 16418686).

Lindheimer, M. D., & Umans, J. G. (2006, September 7). Explaining and predicting preeclampsia. New England Journal of Medicine, 355(10), 1056-1058. (PMID: 16957153).

Nanovskaya, T. N., Nekhayeva, I., Hankins, G. D., & Ahmed, M. S. (2006, August 28). Effect of human serum albumin on transplacental transfer of glyburide. Biochemical Pharmacolog, 72(5), 632-639. (PMID: 16828060).

Nanovskaya, T. N., Nekhayeva, I. A., Patrikeeva, S. L., Hankins, G. D., & Ahmed, M. S. (2006, October). Transfer of metformin across the dually perfused human placental lobule. American Journal of Obstetrics and Gynecology, 195(4), 1081-1085. (PMID: 16824464).

Ravindran, S., Zharikova, O. L., Hill, R. A., Nanovskaya, T. N., Hankins, G. D., & Ahmed, M. S. (2006, December 15). Identification of glyburide metabolites formed by hepatic and placental microsomes of humans and baboons. Biochemical Pharmacology, 72(12), 1730-1737. (PMID: 17011523).

Soldin, O. P. (2006, February). Thyroid function testing in pregnancy and thyroid disease: Trimester-specific reference intervals. Therapeutic Drug Monitoring, 28(1), 8-11. (PMID: 16418685).

Soldin, S. J., Soldin, O. P., Boyajian, A. J., & Taskier, M. S. (2006, April). Pediatric brain natriuretic peptide and N-terminal pro-brain natriuretic peptide reference intervals. Clinica Chimica Acta, 366(1-2), 304-308. (PMID: 16360137).

Presentations

Harirah, H. M., Borahay, M., Wahiduz, Z., Ahmed, M. S., & Hankins, G. D. V. (2006, February). Effect of the contact between the amnion and chorion-decidua layers in human fetal membranes on prostaglandin production. 26th Annual Meeting of the Society for Maternal-Fetal Medicine, Miami, FL.

Harirah, H. M., Zaman, W., Ahmed, M. S., & Hankins, G. D. V. (2006, February). Effect of chorion-decidua on prostaglandin E2 production in human fetal membranes. 26th Annual Meeting of the Society for Maternal-Fetal Medicine, Miami, FL.

Jain, S., Zharikova, O. L., Selvan, R., Nanovskaya, T. N., Hankins, G. D. V., & Ahmed, M. S. (2006, February). Metabolism of glibenclamide (glyburide) by human placenta. 26th Annual Meeting of the Society for Maternal-Fetal Medicine, Miami, FL.

Nekhayeva, I. A., Nanovskaya, T. N., Dziuba, N., Hankins, G. D. V., & Ahmed, M. S. (2006, February). The transfer of glyburide across human placenta obtained from healthy and diabetic patients and the role of human serum albumin. 26th Annual Meeting of the Society for Maternal-Fetal Medicine, Miami, FL.

Patrikeeva, S. L., Hemauer, S. J., Nanovskaya, T. N., Hankins, G. D. V., & Ahmed, M. S. (2006, February). Transplacental transfer and distribution of rosiglitazone. 26th Annual Meeting of the Society for Maternal-Fetal Medicine, Miami, FL.

Ravindran, S., Zharikova, O. L., Hill, R. A., Nanovskaya, T. N., Hankins, G. D. V., & Ahmed, M. S. (2006, February). Metabolism of glyburide by microsomes from human liver and placenta: A study by HPLC-MS. 26th Annual Meeting of the Society for Maternal-Fetal Medicine, Miami, FL.

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